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Pinealon

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Pinealon is a tripeptide (Ala-Glu-Asp) derived from the pineal gland. It is extensively studied in research models for its potential role in regulating circadian rhythms, neuroendocrine function, and cellular aging processes.

It is widely used in studies exploring sleep regulation, hormonal balance, and age-related changes.

Pinealon is a well-researched pineal peptide in research valued for its ability to support circadian rhythm balance, neuroendocrine regulation, and healthy aging pathways.

Pinealon (EDR; Glu–Asp–Arg) is a synthetic tripeptide used in RUO models to probe redox balance, antioxidant signaling, and stress-response transcription. Studies often quantify reactive oxygen species (ROS), Nrf2/ARE pathway readouts, and cross-talk with survival signaling in vitro. Not intended for diagnostic or therapeutic use.

  • Redox balance and antioxidant pathway profiling
  • Stress-response transcriptional signatures
  • Comparative assays vs. non-peptidic antioxidants

Pinealon | Antioxidant & Cellular Signaling

Name Pinealon
Synonyms EDR peptide; Glu-Asp-Arg
Sequence L-Glu–L-Asp–L-Arg (EDR)
Molecular Formula C15H26N6O8
Molecular Weight 418.4 g/mol
CAS Number 175175-23-2
Appearance White to off-white lyophilized powder
Solubility Freely soluble in sterile or bacteriostatic water
Purity ≥99% (HPLC), lot-specific
Storage Guidelines • Lyophilized: ≤0°F (–18°C), dry, protected from light
• Reconstituted: 36–46°F (2–8°C); avoid repeat freeze–thaw
• Long-Term: Keep dry and frozen until use


Ellixon Bio Quality Advantage
  • Purity & Identity: ≥99% | HPLC & MS validated
  • Endotoxin & Sterility: <0.05 EU/mg | Third-party verified
  • Stability & Process: Controlled nucleation lyophilization | Stability-focused procedures
  • Formulation & QA: PhD-Formulated | GMP / ISO-Aligned manufacturing
  • Packaging: Luxe Fridge-Ready Box

Category Overview | Signal Transduction Pathways

Antioxidant & cellular-signaling peptides are used in RUO studies to explore how cells defend against oxidative stress while coordinating internal messages. Models typically track ROS/RNS levels, redox-sensitive transcription, and cross-talk with survival pathways.

Exciting Areas of Study

  • Neutralize ROS in aging and stress-induced in-vitro models.
  • Map antioxidant peptide effects on survival & signaling cascades.
  • Study anti-inflammatory readouts in tissue-model assays.
  • Investigate redox balance and mitochondrial cross-talk.
  • Quantify ROS/RNS and antioxidant enzyme responses

Pinealon | Research Modeling & Applications
  • Track ROS modulation and antioxidant gene activation
  • Evaluate redox-stress resilience across dosing paradigms
  • Compare EDR vs. control peptides in survival assays

Research Use Disclaimer

This product is supplied for laboratory research use only (RUO) and is intended solely for qualified professionals in a controlled research setting. It is not a drug, food, dietary supplement, cosmetic, or medical device, and is not intended for human or veterinary use or for any diagnostic, therapeutic, or clinical application. It is not for household use.

No statement on this page has been evaluated by the U.S. Food and Drug Administration. Nothing herein is intended to diagnose, treat, cure, or prevent any disease, nor to suggest any dosage, route, or method of administration. Ellixon Bio makes no representation or warranty, express or implied, regarding fitness for any purpose other than research and provides no medical or professional advice. The purchaser and end user assume full responsibility for safe handling, storage, and use in accordance with all applicable laws, regulations, and institutional safety protocols, and accept all associated risk and liability.

See our Terms & Conditions and our Research Compliance Disclaimers for complete terms.

Lot numberStrengthAnalysis dateTestingCertificate
EBL-PIN-10-0726-0128-100110 MGAugust 9, 2026Purity & Net Peptide TestingView PDF
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