Tesamorelin Acetate is an N-terminally modified GHRH(1-44) analog used in RUO signal-transduction models to interrogate GPCR-driven cAMP/PKA signaling and CREB-linked transcription. Studies often quantify receptor engagement, second messengers, and downstream gene expression. Not intended for diagnostic or therapeutic use.
- GHRH-R coupling and cAMP kinetics
- PKA/CREB pathway transcriptional readouts
- Comparisons vs. native GHRH and shorter analogs
Tesamorelin Acetate | Molecular Identity & Composition
| Name | Tesamorelin Acetate |
| Synonyms | Tesamorelin; Egrifta; t-3-Hexenoyl-GHRH(1-44)-NH2 |
| Sequence | t-3-Hexenoyl-Tyr-Ala-Asp-Ala-Ile-Phe-Thr-Asn-Ser-Tyr-Arg-Lys-Val-Leu-Gly-Gln-Leu-Ser-Ala-Arg-Lys-Leu-Leu-Gln-Asp-Ile-Met-Ser-Arg-Gln-Gln-Gly-Glu-Ser-Asn-Gln-Glu-Arg-Gly-Ala-Arg-Ala-Arg-Leu-NH2 |
| Molecular Formula | C221H366N72O67S (free base) |
| Molecular Weight | ~5135.8 g/mol (free base) |
| CAS Number | 218949-48-5 (base) |
| Appearance | White to off-white lyophilized powder |
| Solubility | Soluble in sterile water or bacteriostatic water |
| Purity | ≥99% (HPLC) |
| Storage Guidelines | • Lyophilized: ≤0°F (–18°C), dry, protected from light • Reconstituted: 36–46°F (2–8°C); avoid repeat freeze–thaw • Long-Term: Keep dry and frozen until use |
Ellixon Bio Quality Advantage
- Purity & Identity: ≥99% | HPLC & MS validated
- Endotoxin & Sterility: <0.05 EU/mg | Third-party verified
- Stability & Process: Controlled nucleation lyophilization | Stability-focused procedures
- Formulation & QA: PhD-Formulated | GMP / ISO-Aligned manufacturing
- Packaging: Luxe Fridge-Ready Box
Category Overview | Signal Transduction Pathways
Signal transduction peptides are used in RUO studies to explore how cells send and receive messages. These signals help control how cells grow, repair themselves, and respond to stress. Researchers use these peptides in lab models to better understand how communication inside cells works—and what happens when it doesn’t.
Exciting Areas of Study
- How cellular signals initiate chain reactions in lab models.
- Peptide effects on messaging pathways like MAPK & PI3K.
- How cells respond to stress in lab models.
- Model disrupted signaling seen in pre-clinical disease research.
- Map how cell signals change under different conditions
Tesamorelin Acetate | Research Modeling & Applications
- Quantify GHRH-R–cAMP–PKA–CREB signaling chains
- Benchmark transcriptional programs vs. GHRH(1-44)
- Profile bias/kinetics across receptor contexts
Research Use Disclaimer
This product is supplied for laboratory research use only (RUO) and is intended solely for qualified professionals in a controlled research setting. It is not a drug, food, dietary supplement, cosmetic, or medical device, and is not intended for human or veterinary use or for any diagnostic, therapeutic, or clinical application. It is not for household use.
No statement on this page has been evaluated by the U.S. Food and Drug Administration. Nothing herein is intended to diagnose, treat, cure, or prevent any disease, nor to suggest any dosage, route, or method of administration. Ellixon Bio makes no representation or warranty, express or implied, regarding fitness for any purpose other than research and provides no medical or professional advice. The purchaser and end user assume full responsibility for safe handling, storage, and use in accordance with all applicable laws, regulations, and institutional safety protocols, and accept all associated risk and liability.
See our Terms & Conditions and our Research Compliance Disclaimers for complete terms.
