TB-500 refers to research-grade thymosin β4 (timbetasin), used in RUO models to probe cytoskeletal signaling, motility, and matrix remodeling. Typical readouts include actin dynamics, focal-adhesion markers, and migration/closure assays. Not intended for diagnostic or therapeutic use.
- Actin-binding/cytoskeletal signaling
- Cell migration & wound-closure models
- Matrix deposition and remodeling markers
TB-500 | Molecular Identity & Composition
| Name | TB-500 |
| Synonyms | Thymosin β4; Timbetasin; Tβ4; TB-500 |
| Sequence | Ac-Ser-Asp-Lys-Pro-Asp-Met-Ala-Glu-Ile-Glu-Lys-Phe-Asp-Lys-Ser-Lys-Leu-Lys-Lys-Thr-Glu-Thr-Gln-Glu-Lys-Asn-Pro-Leu-Pro-Ser-Lys-Glu-Thr-Ile-Glu-Gln-Glu-Lys-Gln-Ala-Gly-Glu-Ser |
| Molecular Formula | C212H350N56O78S |
| Molecular Weight | ~4963.5 g/mol |
| CAS Number | 77591-33-4 |
| Appearance | White to off-white lyophilized powder |
| Solubility | Soluble in sterile water or bacteriostatic water |
| Purity | ≥99% (HPLC) |
| Storage Guidelines | • Lyophilized: ≤0°F (–18°C), dry, protected from light • Reconstituted: 36–46°F (2–8°C); avoid repeat freeze–thaw • Long-Term: Keep dry and frozen until use |
Ellixon Bio Quality Advantage
- Purity & Identity: ≥99% | HPLC & MS validated
- Endotoxin & Sterility: <0.05 EU/mg | Third-party verified
- Stability & Process: Controlled nucleation lyophilization | Stability-focused procedures
- Formulation & QA: PhD-Formulated | GMP / ISO-Aligned manufacturing
- Packaging: Luxe Fridge-Ready Box
Category Overview | Tissue Remodeling & Protein Function
Tissue-remodeling peptides are used in RUO systems to study how cells organize cytoskeleton and matrix—migration, adhesion, and protein-network balance. These models help profile dynamic protein function under strain, injury, or growth conditions.
Exciting Areas of Study
- Actin turnover, lamellipodia/filopodia dynamics
- ECM production and deposition assays
- Motility, closure, and invasion models
- Cytoskeletal signaling cross-talk (FAK, Rho/ROCK)
- Quantify migration/closure kinetics in vitro
TB-500 | Research Modeling & Applications
- Map actin-binding effects on cytoskeletal architecture
- Evaluate matrix remodeling and adhesion markers
- Compare motility phenotypes across stressors
Research Use Disclaimer
This product is supplied for laboratory research use only (RUO) and is intended solely for qualified professionals in a controlled research setting. It is not a drug, food, dietary supplement, cosmetic, or medical device, and is not intended for human or veterinary use or for any diagnostic, therapeutic, or clinical application. It is not for household use.
No statement on this page has been evaluated by the U.S. Food and Drug Administration. Nothing herein is intended to diagnose, treat, cure, or prevent any disease, nor to suggest any dosage, route, or method of administration. Ellixon Bio makes no representation or warranty, express or implied, regarding fitness for any purpose other than research and provides no medical or professional advice. The purchaser and end user assume full responsibility for safe handling, storage, and use in accordance with all applicable laws, regulations, and institutional safety protocols, and accept all associated risk and liability.
See our Terms & Conditions and our Research Compliance Disclaimers for complete terms.
