VIP is a 28-amino-acid neuropeptide used in RUO models to study GPCR-mediated signal transduction via VPAC1/VPAC2 and downstream cAMP/PKA/CREB responses. Typical assays include receptor selectivity, second-messenger kinetics, and transcriptional mapping. Not intended for diagnostic or therapeutic use.
- VPAC1/VPAC2 engagement and bias profiling
- cAMP/PKA–linked transcriptional outputs
- Signal timing/kinetics under stress paradigms
VIP | Molecular Identity & Composition
Name
VIP
Synonyms
VIP; Vasoactive Intestinal Polypeptide
Sequence
His-Ser-Asp-Ala-Val-Phe-Thr-Asp-Asn-Tyr-Thr-Arg-Leu-Arg-Lys-Gln-Met-Ala-Val-Lys-Lys-Tyr-Leu-Asn-Ser-Ile-Leu-Asn-NH2
Molecular Formula
C147H237N43O43S
Molecular Weight
~3326.8 g/mol
CAS Number
0077-57-4 (human VIP)
Appearance
White to off-white White to off-white lyophilized powder
Solubility
Soluble in sterile or bacteriostatic water
Purity
≥99% (HPLC), lot-specific
Storage Guidelines
• Lyophilized: ≤0°F (–18°C), dry, protected from light
• Reconstituted: 36–46°F (2–8°C); avoid repeat freeze–thaw
• Long-Term: Keep dry and frozen until use
Ellixon Bio Quality Advantage
- Purity & Identity: ≥99% | HPLC & MS validated
- Endotoxin & Sterility: <0.05 EU/mg | Third-party verified
- Stability & Process: Controlled nucleation lyophilization | Stability-focused procedures
- Formulation & QA: PhD-Formulated | GMP / ISO-Aligned manufacturing
- Packaging: Luxe Fridge-Ready Box
Category Overview | Signal Transduction Pathways
Signal transduction peptides are used in RUO studies to explore how cells send and receive messages. These signals help control how cells grow, repair themselves, and respond to stress. Researchers use these peptides in lab models to better understand how communication inside cells works—and what happens when it doesn’t.
Exciting Areas of Study
- How cellular signals initiate chain reactions in lab models.
- Peptide effects on messaging pathways like MAPK & PI3K.
- How cells respond to stress in lab models.
- Model disrupted signaling seen in pre-clinical disease research.
- Map how cell signals change under different conditions
VIP | Research Modeling & Applications
- Profile VPAC1/VPAC2 coupling and bias
- Quantify cAMP–PKA–CREB cascade dynamics
- Benchmark transcriptional signatures vs. agonist controls
Research Use Disclaimer
This product is supplied for laboratory research use only (RUO) and is intended solely for qualified professionals in a controlled research setting. It is not a drug, food, dietary supplement, cosmetic, or medical device, and is not intended for human or veterinary use or for any diagnostic, therapeutic, or clinical application. It is not for household use.
No statement on this page has been evaluated by the U.S. Food and Drug Administration. Nothing herein is intended to diagnose, treat, cure, or prevent any disease, nor to suggest any dosage, route, or method of administration. Ellixon Bio makes no representation or warranty, express or implied, regarding fitness for any purpose other than research and provides no medical or professional advice. The purchaser and end user assume full responsibility for safe handling, storage, and use in accordance with all applicable laws, regulations, and institutional safety protocols, and accept all associated risk and liability.
See our Terms & Conditions and our Research Compliance Disclaimers for complete terms.
