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Semax

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Semax is a synthetic analog of the ACTH(4-10) fragment. It is extensively studied in research models for its potential to support cognitive function, neuroprotection, and neurochemical balance.

It is widely used in studies exploring memory, learning, focus, stress resilience, and overall brain health.

Semax is a powerful nootropic peptide in research valued for its ability to enhance cognitive performance, support neuronal health, and modulate stress responses.

Semax (MEHFPGP) is a heptapeptide analog used in RUO signal-transduction models to interrogate receptor-proximal messaging, stress-response transcription, and plasticity-linked pathways. Studies commonly track early signaling kinetics and downstream transcriptional programs in vitro. Not intended for diagnostic or therapeutic use.

  • Receptor-proximal signal initiation and kinetics
  • Stress-response transcriptional profiling
  • Comparisons vs. capped/amidated analogs

Semax | Antioxidant & Cellular Signaling

Name Semax
Synonyms MEHFPGP; Met-Glu-His-Phe-Pro-Gly-Pro
Sequence H-Met-Glu-His-Phe-Pro-Gly-Pro-OH (MEHFPGP)
Molecular Formula C37H51N9O10S
Molecular Weight 813.9 g/mol
CAS Number 80714-61-0
Appearance White to off-white lyophilized powder
Solubility Soluble in sterile or bacteriostatic water
Purity ≥99% (HPLC), lot-specific
Storage Guidelines • Lyophilized: ≤0°F (–18°C), dry, protected from light
• Reconstituted: 36–46°F (2–8°C); avoid repeat freeze–thaw
• Long-Term: Keep dry and frozen until use


Ellixon Bio Quality Advantage
  • Purity & Identity: ≥99% | HPLC & MS validated
  • Endotoxin & Sterility: <0.05 EU/mg | Third-party verified
  • Stability & Process: Controlled nucleation lyophilization | Stability-focused procedures
  • Formulation & QA: PhD-Formulated | GMP / ISO-Aligned manufacturing
  • Packaging: Luxe Fridge-Ready Box

Category Overview | Signal Transduction Pathways

Signal transduction peptides are used in RUO studies to explore how cells send and receive messages. These signals help control how cells grow, repair themselves, and respond to stress. Researchers use these peptides in lab models to better understand how communication inside cells works—and what happens when it doesn’t.

Exciting Areas of Study

  • How cellular signals initiate chain reactions in lab models.
  • Peptide effects on messaging pathways like MAPK & PI3K.
  • How cells respond to stress in lab models.
  • Model disrupted signaling seen in pre-clinical disease research.
  • Map how cell signals change under different conditions

Semax | Research Modeling & Applications
  • Assess receptor-proximal signaling and transcriptional outputs
  • Benchmark non-capped vs. capped/amidated analogs
  • Evaluate stress-model readouts vs. baseline peptides

Research Use Disclaimer

This product is supplied for laboratory research use only (RUO) and is intended solely for qualified professionals in a controlled research setting. It is not a drug, food, dietary supplement, cosmetic, or medical device, and is not intended for human or veterinary use or for any diagnostic, therapeutic, or clinical application. It is not for household use.

No statement on this page has been evaluated by the U.S. Food and Drug Administration. Nothing herein is intended to diagnose, treat, cure, or prevent any disease, nor to suggest any dosage, route, or method of administration. Ellixon Bio makes no representation or warranty, express or implied, regarding fitness for any purpose other than research and provides no medical or professional advice. The purchaser and end user assume full responsibility for safe handling, storage, and use in accordance with all applicable laws, regulations, and institutional safety protocols, and accept all associated risk and liability.

See our Terms & Conditions and our Research Compliance Disclaimers for complete terms.

Lot numberStrengthAnalysis dateTestingCertificate
EBL-SEM-10-0726-0128-100110 MGAugust 22, 2026Purity & Net Peptide TestingView PDF
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